SATlotyper

Haplotype inference from unphased SNP data in heterozygous polyploids based on SAT
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SATlotyper Ranking & Summary

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  • Rating:
  • License:
  • Freeware
  • Publisher Name:
  • Jost Neigenfind
  • File Size:
  • 1.9 MB

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SATlotyper Description

SATlotyper is a software tool designed for inferring haplotypes from polyploid and polyallelic unphased SNP data. SATlotyper uses Boolean operators and variables to formulate Haplotype Inference by Pure Parsimony (HIPP) for the Boolean Satisfiability Problem (SAT). For finding the most parsimonious set of explaining haplotypes, SATlotyper starts with assuming one explaining haplotype and increases the number of haplotypes until a satisfying set is found. Since SAT is NP-complete, it can not be guaranteed that a solution is found in reasonable time for a given data. However, empiric tests showed that it is possible to calculate inferences for data from real world. Furthermore, SATlotyper gives constraints for alternative explaining solutions and is able to optimize the likelihood of the result by means of a bootstrapping procedure. Give SATlotyper a try to see how useful it can actually be for you!


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